Excessive consumption of manganese: severe heart threat

It is essential to detect manganese found in leafy vegetables, fruits and nuts, in small quantities it is necessary for the development of good work of skeletal, metabolism and thyroid gland.

However, in high doses it can prove to be dangerous for the heart, shows a new scientific study published in cell host and microbes

According to new findings, excessive intake of manganese is associated with the risk of heart infection by bacterial staphylococcus aureus.

Studies seem to strengthen the theory that diet can affect the chances of infection being infected and it also acts as a warning for those people who eat excessive amounts through their food and / or dietary supplements. In the manganese take.

"The human body can regulate the level of different nutrients and there are substantial minerals in the traditional Western diet." The idea of ​​consuming excessive intake should be taken seriously, "the lead author of the study, Eric Schaar of Waddingville University of USA, Is said .

Mark and colleagues studied the effect of manganese taken in the experimental mice through diet and found that when the intake of metal was increased (about three times the normal), the suggestion of animals after the analysis done by the staphylococcus aureus researchers Given that large scale manganese had been received by the animals, especially due to staphflococcus infection in the heart Nbavna was over.

While investigating possible systems due to the above results, researchers found that manganese has disabled critical defense mechanisms against pathogenic microorganisms. In physiological conditions, when the organism is attacked by the staphylococcus, the dissection cells (neutrophil) that release the active forms of oxygen (ROS) are called marks, but when manganese are found in large amounts in the body, then This rescue process does not work. "It's striking how any change in the diet can stop one of the most powerful defense proteins," said Skar.

Staphylococcus infection is the most common cause of bacterial endocarditis (internal infection of the heart) and is the second most common cause of blood transfusion. In subsequent studies, Scarr and colleagues are planning to investigate why the heart is more susceptible to staphylococcus infection in addition to manganese, and if other organisms, such as minerals and vitamins, affect the sensitivity of the infection.